Lamium Plants—A Comprehensive Review on Health Benefits and Biological Activities

Author:

Salehi BahareORCID,Armstrong LoreneORCID,Rescigno AntonioORCID,Yeskaliyeva BalakyzORCID,Seitimova GulnazORCID,Beyatli Ahmet,Sharmeen Jugreet,Mahomoodally Mohamad FawziORCID,Sharopov FarukhORCID,Durazzo AlessandraORCID,Lucarini Massimo,Santini AntonelloORCID,Abenavoli LudovicoORCID,Capasso Raffaele,Sharifi-Rad JavadORCID

Abstract

This work is an updated snapshot of Lamium plants and their biological activities. The main features of the plant are described and the components of its essential oils are summarized. The traditional medicinal uses of Lamium plants has been reported. The presence of these chemicals i.e., hydroxycinnamic acids, iridoids, secoiridoids, flavonoids, anthocyanins, phenylpropanoids, phytoecdysteroids, benzoxazinoids, betaine can provide biological activities. After the discussion of antioxidant properties documented for Lamium plants, the biological activities, studied using in vitro models, antimicrobial, antiviral, anti-inflammatory, anti-nociceptive activity, and pain therapy and cytotoxicity and cytoprotective activity are here described and discussed. Finally, targeted examples of in vivo studies are reported.

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

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