Synthesis of Polyheterocyclic Pyrrolo[3,4-b]pyridin-5-ones via a One-Pot (Ugi-3CR/aza Diels-Alder/N-acylation/aromatization/SN2) Process. A Suitable Alternative towards Novel Aza-Analogues of Falipamil-Reference-Cited by-同舟云学术

Synthesis of Polyheterocyclic Pyrrolo[3,4-b]pyridin-5-ones via a One-Pot (Ugi-3CR/aza Diels-Alder/N-acylation/aromatization/SN2) Process. A Suitable Alternative towards Novel Aza-Analogues of Falipamil

Published:2018-03-27 Issue:4 Volume:23 Page:763
ISSN:1420-3049
Container-title:Molecules
language:en
Short-container-title:Molecules

Author:

Zamudio-Medina Angel,García-González Ailyn,Herrera-Carrillo Genesis,Zárate-Zárate Daniel,Benavides-Macías Adriana,Tamariz Joaquín,Ibarra Ilich,Islas-Jácome Alejandro,González-Zamora Eduardo^ORCID

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

Link

http://www.mdpi.com/1420-3049/23/4/763/pdf

Reference29 articles.

1. Specific bradycardic agents. 1. Chemistry, pharmacology, and structure-activity relationships of substituted benzazepinones, a new class of compounds exerting antiischemic properties

2. Synthesis and bradycardic activity of a series of substituted 3-aminoalkyl-2,3-dihydro-4H-1,3-benzoxazin-4-ones as potent antiischemics

3. Cardiac electrophysiological effects of falipamil in the conscious dog: comparison with alinidine

4. The chemistry of isoindole natural products

5. Enantioselective Synthesis of α‐Secondary and α‐Tertiary Piperazin‐2‐ones and Piperazines by Catalytic Asymmetric Allylic Alkylation

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1. Synthesis of New Spiropyrrolo[3,4-b]Pyridine Derivatives Employed Multicomponent Reactions;Polycyclic Aromatic Compounds;2023-11-30

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3. The Ugi three-component reaction and its variants;Organic Chemistry Frontiers;2021

4. One-pot synthesis of substituted pyrrolo[3,4-b]pyridine-4,5-diones based on the reaction of N-(1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-2-oxo-2-arylethyl)acetamide with amines;Beilstein Journal of Organic Chemistry;2019-11-25

5. Pharmacology of Ivabradine and the Effect on Chronic Heart Failure;Current Topics in Medicinal Chemistry;2019-10-28