Analysis of Molar Substitution of Hydroxybutyl Group by Zeisel Reaction in Starch Ethers

Author:

Man Xiao-Lei,Peng Wei-Kang,Chen Jun,Liu Xue-Li

Abstract

A new etherified starch, δ-hydroxybutyl starch (δ-HBS), was prepared by utilising 4-chlorobutan-1-ol as the etherifying reagent. The method of Zeisel gas chromatography for the determination of the molar substitution was described. This technique offers a simple and rapid method for quantitative analysis with reproducible results. Meanwhile, the mechanism of the Zeisel reaction was also investigated.

Funder

the Scientific Research Start Foundation Project of Chuzhou University

University Natural Science Research Project of Anhui Province

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

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