Pullulan-Graft-Polyoxazoline: Approaches from Chemistry and Physics

Author:

Zorin Ivan M.1ORCID,Fetin Petr A.1ORCID,Mikusheva Nina G.2ORCID,Lezov Alexey A.2ORCID,Perevyazko Igor2,Gubarev Alexander S.2ORCID,Podsevalnikova Anna N.2,Polushin Sergey G.2,Tsvetkov Nikolai V.2ORCID

Affiliation:

1. Institute of Chemistry, Saint-Petersburg State University, Universitetskaya Nab. 7/9, 199034 Saint-Petersburg, Russia

2. Department of Molecular Biophysics and Polymer Physics, Saint-Petersburg State University, Universitetskaya Nab. 7/9, 199034 Saint-Petersburg, Russia

Abstract

An approach to the preparation of pullulan-graft-poly(2-methyl-2-oxazoline)s based on Cu-catalyzed azide–alkyne cycloaddition with polyoxazoline-azide was applied. All of the obtained polymers were characterized through classical molecular hydrodynamic methods and NMR. The formation of graft copolymers was accomplished by oxidative degradation of pullulan chains. Nevertheless, graft copolymers were obtained as uniform products with varied side chain lengths and degrees of substitution.

Funder

Russian Science Foundation

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

Reference64 articles.

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