Rapid and Sensitive LC-MS/MS Method for the Determination of Metoprolol in Beagle Dog Plasma with a Simple Protein Precipitation Treatment and Its Pharmacokinetic Applications

Author:

Li Sha,Wang Xingli,Peng Kelong,Ma Zhiguo,Zhang Xiaoqi,Fu Shaolian,Li Xiaofei,Li Linlin,Hong Aihua,Jiang Jie

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

Reference20 articles.

1. Quantitative determination of metoprolol by liquid chromatography mass spectrometry in rat plasma;Zhang;Bull. Acad. Mil. Med. Sci.,2009

2. Studies on explosion pulsatile-release tablets of metoprolol fumarate in vitro;Gu;Chin. Pharm. J.,2006

3. Pulsatile multiparticulate drug delivery system for metoprolol succinate

4. Determination of metoprolol, and its four metabolites in dog plasma

5. The study of pharmacokinetics of metoprolol succinate sustained release tablets in dogs;Huang;J. Shandong Univ. (Health Sci.),2004

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