Solvent-Free Addition of Indole to Aldehydes: Unexpected Synthesis of Novel 1-[1-(1H-Indol-3-yl) Alkyl]-1H-Indoles and Preliminary Evaluation of Their Cytotoxicity in Hepatocarcinoma Cells-Reference-Cited by-同舟云学术

Solvent-Free Addition of Indole to Aldehydes: Unexpected Synthesis of Novel 1-[1-(1H-Indol-3-yl) Alkyl]-1H-Indoles and Preliminary Evaluation of Their Cytotoxicity in Hepatocarcinoma Cells

Published:2017-10-17 Issue:10 Volume:22 Page:1747
ISSN:1420-3049
Container-title:Molecules
language:en
Short-container-title:Molecules

Author:

Tocco Graziella,Zedda Gloria,Casu Mariano,Simbula Gabriella^ORCID,Begala Michela

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

Link

http://www.mdpi.com/1420-3049/22/10/1747/pdf

Reference40 articles.

1. Indoles;Joule,2011

2. An Update on Catalytic Enantioselective Alkylations of Indoles

3. Computer-Aided Rational Drug Design: A Novel Agent (SR13668) Designed to Mimic the Unique Anticancer Mechanisms of Dietary Indole-3-Carbinol to Block Akt Signaling

4. Anticancer activity of synthetic bis(indolyl)methane-ortho-biaryls against human cervical cancer (HeLa) cells

5. Indole-3-carbinol as a chemopreventive and anti-cancer agent

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