Affiliation:
1. Faculty of Chemical Technology, Poznan University of Technology, Berdychowo 4, PL-60965 Poznan, Poland
2. Department of Pharmaceutical Technology, Faculty of Pharmacy, Nicolaus Copernicus University, Jurasza 2, PL-85089 Bydgoszcz, Poland
Abstract
The present work provides new evidence of the ongoing potential of surface-active ionic liquids (SAILs) and surface-active quaternary ammonium salts (surface-active QASs). To achieve this, a series of compounds were synthesized with a yield of ≥85%, and their thermal analyses were studied. Additionally, antimicrobial activity against both human pathogenic and soil microorganisms was investigated. Subsequently, their surface properties were explored with the aim of utilizing SAILs and surface-active QASs as alternatives to commercial amphiphilic compounds. Finally, we analyzed the wettability of the leaves’ surface of plants occurring in agricultural fields at different temperatures (from 5 to 25 °C) and the model plant membrane of leaves. Our results show that the synthesized compounds exhibit higher activity than their commercial analogues such as, i.e., didecyldimethylammonium chloride (DDAC) and dodecyltrimethylammonium bromide (C12TAB), for which the CMC values are 2 mM and 15 mM. The effectiveness of the antimicrobial properties of synthesized compounds relies on their hydrophobic nature accompanied by a cut-off effect. Moreover, the best wettability of the leaves’ surface was observed at 25 °C. Our research has yielded valuable insights into the potential effectiveness of SAILs and surface-active QASs as versatile compounds, offering a promising alternative to established antimicrobials and crop protection agents, all the while preserving substantial surface activity.
Funder
Ministry of Education and Science in Poland
Subject
Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science
Reference57 articles.
1. Ali, M.K., Moshikur, R.M., and Goto, M. (2021). Application of Ionic Liquids in Drug Delivery, Springer.
2. Synthesis and Characterization of Surface-Active Ionic Liquids for Their Potential Application in Enhanced Oil Recovery;Pillai;J. Mol. Liq.,2022
3. Surface-Active Ionic Liquids: A Review;Buettner;J. Mol. Liq.,2022
4. Rosen, M.J. (2004). Surfactants and Interfacial Phenomena, John Wiley & Sons, Inc.
5. Evaluation of Antimicrobial Properties of Monocationic and Dicationic Surface-Active Ionic Liquids;Wojcieszak;J. Mol. Liq.,2023