Characteristic Photoprotective Molecules from the Sphagnum World: A Solution-Phase Ultrafast Study of Sphagnic Acid-Reference-Cited by-同舟云学术

Characteristic Photoprotective Molecules from the Sphagnum World: A Solution-Phase Ultrafast Study of Sphagnic Acid

Published:2023-08-21 Issue:16 Volume:28 Page:6153
ISSN:1420-3049
Container-title:Molecules
language:en
Short-container-title:Molecules

Author:

Hymas Michael¹,Casademont-Reig Irene¹²^ORCID,Poigny Stéphane³,Stavros Vasilios G.¹⁴

Affiliation:

1. Department of Chemistry, University of Warwick, Coventry CV4 7AL, UK

2. Department of General Chemistry (ALGC), Vrije Universiteit Brussel (VUB), Pleinlaan 2, 1050 Brussels, Belgium

3. Mibelle Group Biochemistry, Mibelle AG, Bolimattstrasse 1, CH-5033 Buchs, Switzerland

4. School of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

Abstract

A natural UV-absorbing chromophore extracted from sphagnum mosses, sphagnic acid, is proposed as a new natural support to chemical UV filters for use in cosmetic applications. Sphagnic acid is structurally related to the cinnamate family of molecules, known for their strong UV absorption, efficient non-radiative decay, and antioxidant properties. In this study, transient electronic absorption spectroscopy is used, in conjunction with steady-state techniques, to model the photodynamics following photoexcitation of sphagnic acid in different solvent systems. Sphagnic acid was found in each system to relax with lifetimes of ~200 fs and ~1.5 ps before generating a cis-isomer photoproduct. This study helps to elucidate the photoprotective mechanism of a new potential natural support to sunscreens, from a unique plant source.

Funder

Central England NERC Training Alliance

Maria Skłodowska-Curie Actions

European Union’s Horizon 2020

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

Link

https://www.mdpi.com/1420-3049/28/16/6153/pdf

Reference54 articles.

1. Solar ultraviolet radiation at the earth’s surface;Frederick;Photochem. Photobiol.,1989

2. Adverse Effects of Ultraviolet Radiation: A Brief Review;Gallagher;Prog. Biophys. Mol. Biol.,2006

3. Early Events in UV Carcinogenesis—DNA Damage, Target Cells and Mutant P53 Foci;Rebel;Photochem. Photobiol.,2008

4. Photoprotection;Lautenschlager;Lancet,2007

5. Inorganic and Organic UV Filters: Their Role and Efficacy in Sunscreens and Suncare Products;Serpone;Inorganica Chim. Acta,2007