Spondias sp: Shedding Light on Its Vast Pharmaceutical Potential

Author:

Santos Érica Mendes dos1ORCID,Ataide Janaína Artem1ORCID,Coco Julia Cedran1ORCID,Fava Ana Laura Masquetti2,Silvério Luiza Aparecida Luna1,Sueiro Ana Claudia1ORCID,Silva Jéssica Ribeiro Alves1,Lopes André Moreni1ORCID,Paiva-Santos Ana Cláudia34ORCID,Mazzola Priscila Gava1ORCID

Affiliation:

1. Faculty of Pharmaceutical Sciences, University of Campinas (Unicamp), Rua Cândido Portinari, 200, Campinas, São Paulo 13083-871, Brazil

2. School of Medical Sciences, University of Campinas (Unicamp), Rua Tessália Vieira de Camargo, 126, Campinas, São Paulo 13083-887, Brazil

3. Department of Pharmaceutical Technology, Faculty of Pharmacy of the University of Coimbra, University of Coimbra, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal

4. LAQV, REQUIMTE, Department of Pharmaceutical Technology, Faculty of Pharmacy of the University of Coimbra, University of Coimbra, Azinhaga Sta. Comba, 3000-548 Coimbra, Portugal

Abstract

Many plants are used by the population through popular knowledge passed from generation to generation for the treatment of various diseases. However, there is not always any scientific content supporting these uses, which is very important for safety. One of these plants is the fruit of the Spondias genus, which during its processing generates various residues that are discarded, but which also have pharmacological properties. The focus of this review is to survey the pharmacological activities that Spondias genus shows, as well as which part of the plant is used, since there is a lot of richness in its by-products, such as leaf, bark, resin, seed, and peel, which are discarded and could be reused. The main activities of this genus are antioxidant, anti-inflammatory, antidiabetic, antifungal, and antiviral, among others. These properties indicate that this genus could be used in the treatment of several diseases, but there are still not many products available on the market that use this genus as an active ingredient.

Funder

Fundação de Amparo à Pesquisa do Estado de São Paulo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior—Brasil

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

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