Affiliation:
1. Department of Chemistry and Industrial Chemistry, University of Pisa, Via Giuseppe Moruzzi 13, 56124 Pisa, Italy
2. Istituto Nazionale di Ottica (INO-CNR) Area di Pisa, Centro Nazionale delle Ricerche, Via Moruzzi, 56124 Pisa, Italy
Abstract
Lewis/Brønsted acidic deep eutectic solvents (LBDESs) are a recent class of solvents that combine the two types of acidity. In some cases, this synergy leads to enhanced catalytic properties for many reactions and applications. For this reason, it is important to discover more LBDESs. In this work, we prepared and characterized four different zinc(II)-based LBDESs, mixing ZnCl2 and various Brønsted acids: acetic, glycolic, levulinic, and formic acids. Apart from the latter, for which the corresponding DES is not thermally stable, the samples have been characterized in terms of density, viscosity, and conductivity. Notably, as zinc(II) is a diamagnetic metal, all of them are suitable for NMR spectroscopy, for example, for kinetic and mechanistic studies.
Subject
Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science
Reference52 articles.
1. Burgess, J.R., and Prince, H. (2006). Encyclopedia of Inorganic and Bioinorganic Chemistry, John Wiley & Sons, Ltd.. [1st ed.].
2. Recent Developments by Zinc Based Reagents/Catalysts Promoted Organic Transformations;Ghouse;Tetrahedron,2022
3. Enhancement of Catalytic Activity of ZnCl2 in the Friedel–Crafts Benzylation of Benzenes Using Polar Solvents;Hayashi;Bull. Chem. Soc. Jpn.,1993
4. Green Synthesis of Substituted Dihydropyrimidin-2(1H)-One by Using Zinc Chloride /Acetic Acid Catalytic System;Thorat;Curr. Chin. Chem.,2020
5. Catalytic, Z-Selective, Semi-Hydrogenation of Alkynes with a Zinc-Anilide Complex;Baker;J. Am. Chem. Soc.,2023