One-Pot Synthesis of Polynuclear Indole Derivatives by Friedel–Crafts Alkylation of γ-Hydroxybutyrolactams-Reference-Cited by-同舟云学术

One-Pot Synthesis of Polynuclear Indole Derivatives by Friedel–Crafts Alkylation of γ-Hydroxybutyrolactams

Published:2023-04-02 Issue:7 Volume:28 Page:3162
ISSN:1420-3049
Container-title:Molecules
language:en
Short-container-title:Molecules

Author:

Abaev Vladimir T.¹²,Aksenov Nicolai A.²^ORCID,Aksenov Dmitrii A.²^ORCID,Aleksandrova Elena V.²,Akulova Alesia S.²,Kurenkov Igor A.²^ORCID,Leontiev Alexander V.²^ORCID,Aksenov Alexander V.²^ORCID

Affiliation:

1. Department of Chemistry, Biology and Biotechnology, North-Ossetian State University Named after K. L. Khetagurov, 46 Vatutin St., Vladikavkaz 362025, Russia

2. Department of Chemistry, North Caucasus Federal University, 1a Pushkin St., Stavropol 355009, Russia

Abstract

The Friedel–Crafts reaction of novel 3,5-diarylsubstituted 5-hydroxy-1,5-dihydro-2H-pyrrol-2-ones was used for low cost, one-pot preparation of polycyclic indole derivatives structurally similar to Ergot alkaloids.

Funder

Russian Science Foundation

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

Link

https://www.mdpi.com/1420-3049/28/7/3162/pdf

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