Diversity-Orientated Synthesis and Biological Properties of Compounds Based on the N-Phenylquinoneimine Scaffold-Reference-Cited by-同舟云学术

Diversity-Orientated Synthesis and Biological Properties of Compounds Based on the N-Phenylquinoneimine Scaffold

Published:2024-01-03 Issue:1 Volume:29 Page:249
ISSN:1420-3049
Container-title:Molecules
language:en
Short-container-title:Molecules

Author:

Adesina Adebimpe¹^ORCID,Skouta Rachid²³^ORCID

Affiliation:

1. Department of Chemistry, Federal University of Agriculture, Abeokuta 111101, Nigeria

2. Department of Biology, University of Massachusetts, Amherst, MA 01003, USA

3. Department of Chemistry, University of Massachusetts, Amherst, MA 01003, USA

Abstract

The N-phenylquinoneimine scaffold is a versatile synthetic platform that has gained significant attention in the field of drug discovery due to its structural diversity and capacity to interact with biologically relevant targets. This review explores established synthetic methodologies and highlights the significant biological activities exhibited by compounds derived from this scaffold, their implications for medicinal chemistry, and the development of novel therapeutics.

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

Link

https://www.mdpi.com/1420-3049/29/1/249/pdf

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