The Advancement of Nanomaterials for the Detection of Hepatitis B Virus and Hepatitis C Virus

Author:

Shi Wanting1,Li Kang2,Zhang Yonghong1

Affiliation:

1. Interventional Therapy Center of Liver Disease, Beijing You’An Hospital, Capital Medical University, Beijing 100069, China

2. Biomedical Information Center, Beijing You’An Hospital, Capital Medical University, Beijing 100069, China

Abstract

Viral hepatitis is a global health concern mostly caused by hepatitis B virus (HBV) and hepatitis C virus (HCV). The late diagnosis and delayed treatment of HBV and HCV infections can cause irreversible liver damage and the occurrence of cirrhosis and hepatocellular carcinoma. Detecting the presence and activity of HBV and HCV is the cornerstone of the diagnosis and management of related diseases. However, the traditional method shows limitations. The utilization of nanomaterials has been of great significance in the advancement of virus detection technologies due to their unique mechanical, electrical, and optical properties. Here, we categorized and illustrated the novel approaches used for the diagnosis of HBV and HCV.

Funder

Beijing Hospitals Authority Youth Programme

National Key R&D Program of China

Capital’s Funds of Health Improvement and Research

Beijing Municipal Science & Technology Commission

Beijing Key Laboratory

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

Reference75 articles.

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2. Global burden of liver disease: 2023 update;Devarbhavi;J. Hepatol.,2023

3. World Health Organization (2017, April 01). Hepatitis B. Fact. Sheet 204, 2017, Available online: https://www.who.int/teams/health-product-policy-and-standards/standards-and-specifications/vaccine-standardization/hep-b.

4. World Health Organization (2021, July 15). Global Progress Report on HIV, Viral Hepatitis and Sexually Transmitted Infections. 2021, Available online: https://apps.who.int/iris/bitstream/handle/10665/341412/9789240027077-eng.pdf.

5. Nguyen, M.H., Wong, G., Gane, E., Kao, J.H., and Dusheiko, G. (2020). Hepatitis B Virus: Advances in Prevention, Diagnosis, and Therapy. Clin. Microbiol. Rev., 33.

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