Resin Glycosides from Convolvulaceae Family: An Update

Author:

Maharani Rani,Fajar MohamadORCID,Supratman Unang

Abstract

Resin glycoside is a type of secondary metabolite isolated commonly from the Convolvulaceae family. It consists of oligosaccharides conjugated to organic acids with a larger percentage having a macrocyclic structure. The resin glycosides reported in this review is classified mostly based on the number of sugar units constructing the structure, which is correlated to the biological properties of the compounds. According to preliminary reviews, the protocols to isolate the compounds are not straightforward and require a special technique. Additionally, the structural determination of the isolated compounds needs to minimize the structure for the elucidation to become easier. Even though resin glycosides have a complicated structural skeleton, several total syntheses of the compounds have been reported in articles published from 2010 to date. This review is an update on the prior studies of the resin glycosides reported in 2010 and 2017. The review includes the classification, isolation techniques, structural determination, biological properties, and total synthesis of the resin glycosides.

Funder

Ministry of Education and Culture, Indonesia

Unang Supratman

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

Reference97 articles.

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3. Multidrug Resistance-Reversal Effects of Resin Glycosides from Dichondra repens;Bioorg. Med. Chem. Lett.,2015

4. Unusual Ether-Type Resin Glycoside Dimers from the Seeds of Cuscuta chinensis;Tetrahedron,2014

5. Resin Glycosides from Porana duclouxii;J. Asian Nat. Prod. Res.,2014

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