Chlamydomonas reinhardtii: A Factory of Nutraceutical and Food Supplements for Human Health

Author:

Masi Annalisa1ORCID,Leonelli Francesca2ORCID,Scognamiglio Viviana1ORCID,Gasperuzzo Giulia1,Antonacci Amina1,Terzidis Michael A.3ORCID

Affiliation:

1. Institute of Crystallography, National Research Council, 00010 Montelibretti, Italy

2. Department of Chemistry, University of Rome “Sapienza”, 00185 Rome, Italy

3. Department of Nutritional Sciences and Dietetics, International Hellenic University, Sindos Campus, 57400 Thessaloniki, Greece

Abstract

Chlamydomonas reinhardtii (C. reinhardtii) is one of the most well-studied microalgae organisms that revealed important information for the photosynthetic and metabolic processes of plants and eukaryotes. Numerous extensive studies have also underpinned its great potential as a biochemical factory, capable of producing various highly desired molecules with a direct impact on human health and longevity. Polysaccharides, lipids, functional proteins, pigments, hormones, vaccines, and antibodies are among the valuable biomolecules that are produced spontaneously or under well-defined conditions by C. reinhardtii and can be directly linked to human nutrition and diet. The aim of this review is to highlight the recent advances in the field focusing on the most relevant applications related to the production of important biomolecules for human health that are also linked with human nutrition and diet. The limitations and challenges are critically discussed along with the potential future applications of C. reinhardtii biomass and processed products in the field of nutraceuticals and food supplements. The increasing need for high-value and low-cost biomolecules produced in an environmentally and economy sustainable manner also underline the important role of C. reinhardtii.

Funder

POR FESR Progetti Gruppi di Ricerca Lazio Innova NYMPHA

Research, Technological Innovation, Telematic Networks (APQ6) DTC TE1 intervention ON-TECH

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

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