Scandium Radioisotopes—Toward New Targets and Imaging Modalities

Author:

Kilian Krzysztof1ORCID,Pyrzyńska Krystyna2ORCID

Affiliation:

1. Heavy Ion Laboratory, University of Warsaw, Pasteura 5a, 02-093 Warsaw, Poland

2. Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland

Abstract

The concept of theranostics uses radioisotopes of the same or chemically similar elements to label biological ligands in a way that allows the use of diagnostic and therapeutic radiation for a combined diagnosis and treatment regimen. For scandium, radioisotopes -43 and -44 can be used as diagnostic markers, while radioisotope scandium-47 can be used in the same configuration for targeted therapy. This work presents the latest achievements in the production and processing of radioisotopes and briefly characterizes solutions aimed at increasing the availability of these radioisotopes for research and clinical practice.

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

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