Abstract
We herein address the problem of polymorph selection by introducing a general and straightforward concept based on their ordering. We demonstrated the concept by the ordered patterning of four compounds capable of forming different polymorphs when deposited on technologically relevant surfaces. Our approach exploits the fact that, when the growth of a crystalline material is confined within sufficiently small cavities, only one of the possible polymorphs is generated. We verify our method by utilizing several model compounds to fabricate micrometric “logic patterns” in which each of the printed pixels is easily identifiable as comprising only one polymorph and can be individually accessed for further operations.
Funder
Ministero Italiano dell’Università e della ricerca.
Subject
Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science
Reference37 articles.
1. Bernstein, J. Polymorphism in Molecular Crystals, 2002.
2. Polymorphism: The Same and Not Quite the Same;Desiraju;Cryst. Growth Des.,2008
3. Qian, W., Xue, X., Liu, J., and Zhang, C. Molecular Forcefield Methods for Describing Energetic Molecular Crystals: A Review. Molecules, 2022. 27.
4. Polymorphism as an additional functionality of materials for technological applications at surfaces and interfaces;Gentili;Chem. Soc. Rev.,2019
5. Conformational Polymorphism;Cruz-Cabeza;Chem. Rev.,2014
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献