Abstract
Immobilized poly(ethylene glycol) (PEG 600-PS) was used as an effective phase-transfer catalyst for the synthesis of hydroxypivaldehyde from isobutyraldehyde (IBA) and formaldehyde in the presence of an inorganic base. Studies on the influence of the parameters on the course of the reaction in a batch reactor showed that the use of the PEG 600-PS catalyst allowed one to obtain HPA with high efficiency (IBA conversion >96%, selectivity >98%) in a relatively short time and under mild conditions (2 h, 40 °C). The developed method enables easy separation of the post-reaction mixture by simple phase separation, and the immobilized catalyst can be separated by filtration and then used five times without a loss in its activity. The high activity and stability of the catalyst was also confirmed in a test carried out in a flow reactor.
Funder
Ministry of Education and Science of Poland
Subject
Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science
Reference33 articles.
1. Hydroxypivaldehyde Synthesis with a Static Mixer Continuous Flow Reactor;Bhaumik;WO Patent,2020
2. A sustainable valorization of neopentyl glycol salt waste containing sodium formate via bipolar membrane electrodialysis
3. Powder Coating Composition Comprising a Polyester and a β-Hydroxyalkylamide as Crosslinker;Buijssen;Patent US,2015
4. Curable Polyester Polyols and Their Use in Thermosetting Soft Feel Coating Formulations;Zhou;Patent US,2018
5. Synteza i zastosowanie aldehydu hydroksypiwalowego
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献