Author:
Cheng Fei,Wu Jianping,Zhang Yan,Wang Yuyan,Li Guihua,Zeng Hongliang,He Xiaoai,Deng Guiming,Tan Jianbin,Long Hongping,Zeng Puhua,Liu Yiheng,Zhu Gangzhi,Chen Zuhui,Xu Kangping
Abstract
Five new furofurans lignans, Brasesquilignan A–E (1–5), were isolated from the aqueous ethanol extract of Selaginella braunii Baker. Their structures were elucidated by extensive analysis of NMR and HRESIMS data. Their absolute configurations were determined by CD spectra, enzymatic hydrolysis, and GCMS analysis. Furthermore, all compounds were evaluated for anti-proliferative activities against various human cancer cellsin vitro. Compounds 2 and 3 exhibited weak inhibitorypotency against five human cancer cells.
Funder
Construction Program of Hunan’s innovative Province (CN)-High-tech Industry Science and Technology Innovation Leading Project
Subject
Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science
Cited by
1 articles.
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