Protection of α-Tocopherol from UV-Induced Degradation by Encapsulation into Zein Nanoparticles

Author:

Kim Sanghoon1ORCID

Affiliation:

1. Plant Polymer Research Unit, National Center for Agricultural Utilization Research, Agricultural Research Service, USDA, 1815 N. University Street, Peoria, IL 61604, USA

Abstract

Vitamin E is a fat-soluble vitamin with several forms. Among these, α-tocopherol (TOC) is preferentially absorbed and accumulated in humans. In the body, it acts as an antioxidant, helping to protect cells from the damage caused by free radicals. It is an organic chemical compound that undergoes degradation upon irradiation with UV light. To protect this bioactive chemical compound from UV light degradation, encapsulation was carried out using zein as a shell material. Due to the unique phase diagram of TOC in aqueous ethanol, the encapsulation efficiency was >99%. The size of encapsulated particles was ~300 nm or smaller, and the thickness of the shell wall was ~30 nm. The presented procedure offers the most simple and efficient encapsulation process that yields edible products. The investigation of the irradiation effect of UV on TOC revealed that the encapsulation effectively blocks UV light and prevents TOC from being degraded. The presented procedure offers an instantaneous and highly efficient encapsulation process, which yields edible products.

Funder

U.S. Department of Agriculture, Agricultural Research Service

Publisher

MDPI AG

Reference25 articles.

1. Encapsulation of a-tocopherol in large-ring cyclodextrin containing 26 a-D-glucopyranose units: A molecular dynamics study;Kerdpol;J. Mol. Liq.,2021

2. Assessment of bioactive compound variations and in-vitro and in-vivo antioxidant activity in edible fresh and processed Bambusa nutans shoot through FTIR, GC/MS and HPLC analyses;Indira;Food Chem.,2023

3. Combs, G.F., and McClung, J.P. (2022). The Vitamins, Elsevier. [6th ed.]. Chapter 7.

4. Malavolta, M., and Mocchegiani, E. (2016). Testing the Ability of Selenium and Vitamin E to Prevent Prostate Cancer in a Large Randomized Phase III Clinical Trial: The Selenium and Vitamin E Cancer Prevention Trial. Molecular Basis of Nutrition and Aging, Elsevier.

5. Interventional study with vitamin E in cardiovascular disease and meta-analysis;Nocella;Free Radic. Biol. Med.,2022

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3