Research Progress on the Mechanism of the Antitumor Effects of Cannabidiol-Reference-Cited by-同舟云学术

Research Progress on the Mechanism of the Antitumor Effects of Cannabidiol

Published:2024-04-24 Issue:9 Volume:29 Page:1943
ISSN:1420-3049
Container-title:Molecules
language:en
Short-container-title:Molecules

Author:

Ma Li¹,Liu Mengke¹,Liu Chuntong¹,Zhang Huachang¹,Yang Shude²^ORCID,An Jing³,Qu Guiwu⁴,Song Shuling¹,Cao Qizhi¹

Affiliation:

1. Department of Immunology, School of Basic Medical Sciences, Binzhou Medical University, Yantai 264003, China

2. Department of Edible Mushrooms, School of Agriculture, Ludong University, Yantai 264025, China

3. Division of Infectious Diseases and Global Health, School of Medicine, University of California San Diego (UCSD), La Jolla, CA 92037, USA

4. Department of Traditional Chinese Medicine, School of Pharmacy, Binzhou Medical University, Yantai 264003, China

Abstract

Cannabidiol (CBD), a non-psychoactive ingredient extracted from the hemp plant, has shown therapeutic effects in a variety of diseases, including anxiety, nervous system disorders, inflammation, and tumors. CBD can exert its antitumor effect by regulating the cell cycle, inducing tumor cell apoptosis and autophagy, and inhibiting tumor cell invasion, migration, and angiogenesis. This article reviews the proposed antitumor mechanisms of CBD, aiming to provide references for the clinical treatment of tumor diseases and the rational use of CBD.

Funder

National Natural Science Foundation of China

Shandong Provincial Natural Science Foundation Joint Fund

Youth Innovation and Technology Support Program in Colleges and Universities of Shandong Province

Yantai Science and Technology Plan Project

Publisher

MDPI AG

Link

https://www.mdpi.com/1420-3049/29/9/1943/pdf

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