Synthesis and Application of Salicylhydrazone Probes with High Selectivity for Rapid Detection of Cu2+

Author:

Shi Tianzhu12,Xie Zhengfeng2,Mo Xinliang1,Feng Yulong1,Peng Tao1,Wu Fuyong1,Yu Mei1,Zhao Jingjing1,Zhang Li1,Guo Ju1

Affiliation:

1. Department of Brewing Engineering, Moutai Institute, Renhuai 564500, China

2. Oil & Gas Field Applied Chemistry Key Laboratory of Sichuan Province, College of Chemistry and Chemical Engineering, Southwest Petroleum University, Chengdu 610500, China

Abstract

Using the aldehyde amine condensation procedure and the triphenylamine group as the skeleton structure, the new triphenylamine-aromatic aldehyde-succinylhydrazone probe molecule DHBYMH was created. A newly created acylhydrazone probe was structurally characterized by mass spectrometry (MS), NMR, and infrared spectroscopy (FTIR). Fluorescence and UV spectroscopy were used to examine DHBYMH’s sensing capabilities for metal ions. Notably, DHBYMH achieved a detection limit of 1.62 × 10−7 M by demonstrating exceptional selectivity and sensitivity towards Cu2+ ions in an optimum sample solvent system (DMSO/H2O, (v/v = 7/3); pH = 7.0; cysteine (Cys) concentration: 1 × 10−4 M). NMR titration, high-resolution mass spectrometry analysis, and DFT computation were used to clarify the response mechanism. Ultimately, predicated on DHBYMH’s reversible identification of Cu2+ ions in the presence of EDTA, a molecular logic gate was successfully designed.

Funder

Zunyi Outstanding Youth Science and Technology Innovation Talents Training Project

Moutai Institute Joint Science and Technology Research and Development Project

Modern Baijiu Brewing Technology Engineering Research Center of Guizhou Universities, Qianjiaoji

Zunyi Science and Technology Bureau of Guizhou Province and Moutai Institute Joint Science and Technology Cooperation Fund Project, Zunyi Ke

Research Foundation for Scientific Scholars of Moutai Institute

Guizhou Province Distillers Grain and Agricultural Waste Resource Utilization Engineering Research Center

A Project on Characteristic Key Laboratory of Guizhou Ordinary Colleges and Universities by the Department of Education of Guizhou Province

Guizhou Engineering Research Center for Comprehensive Utilization of Distillers’ Grains

Publisher

MDPI AG

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