Abstract
Surface-enhanced Raman scattering (SERS) is a widely used technique for drug detection due to high sensitivity and molecular specificity. The applicability and selectivity of SERS in the detection of specific drug molecules can be improved by gathering information on the specific interactions occurring between the molecule and the metal surface. In this work, multilayer gold-silver bimetallic nanorods (Au@Ag@AuNRs) have been prepared and used as platforms for SERS detection of specific drugs (namely promethazine, piroxicam, furosemide and diclofenac). The analysis of SERS spectra provided accurate information on the molecular location upon binding and gave some insight into molecule-surface interactions and selectivity in drug detection through SERS.
Subject
Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science
Cited by
23 articles.
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