Morpholine, Piperazine, and Piperidine Derivatives as Antidiabetic Agents

Author:

Zolotareva Darya1,Zazybin Alexey1,Dauletbakov Anuar1,Belyankova Yelizaveta1ORCID,Giner Parache Beatriz2ORCID,Tursynbek Saniya1ORCID,Seilkhanov Tulegen3ORCID,Kairullinova Anel1

Affiliation:

1. School of Chemical Engineering, Kazakh-British Technical University, 59 Tole bi Str., Almaty 050000, Kazakhstan

2. Facultad de Ciencias de la Salud, Universidad San Jorge, 50830 Zaragoza, Spain

3. Laboratory of Engineering Profile NMR Spectroscopy, Sh. Ualikhanov Kokshetau University, 76 Abay Str., Kokshetau 020000, Kazakhstan

Abstract

Diabetes mellitus is a severe endocrine disease that affects more and more people every year. Modern medical chemistry sets itself the task of finding effective and safe drugs against diabetes. This review provides an overview of potential antidiabetic drugs based on three heterocyclic compounds, namely morpholine, piperazine, and piperidine. Studies have shown that compounds containing their moieties can be quite effective in vitro and in vivo for the treatment of diabetes and its consequences.

Funder

Ministry of Science and Higher Education of the Republic of Kazakhstan

Publisher

MDPI AG

Reference47 articles.

1. Brutsaert, E.F., and Diabetes Mellitus (DM) (2024, May 11). MSD Manual. Available online: https://www.msdmanuals.com/en-gb/professional/endocrine-and-metabolic-disorders/diabetes-mellitus-and-disorders-of-carbohydrate-metabolism/diabetes-mellitus-dm?query=Diabetes%20Mellitus%20(DM).

2. Global Burden of Disease Collaborative Network (2024, May 11). Global Burden of Disease Study 2019. Results. Institute for Health Metrics and Evaluation. Available online: https://vizhub.healthdata.org/gbd-results/.

3. Insuline Basics (2024, May 11). American Diabetes Association. Available online: https://diabetes.org/healthy-living/medication-treatments/insulin-other-injectables/insulin-basics.

4. Gardner, D.G., and Shoback, D. (2011). Chapter 17. Pancreatic Hormones and Diabetes Mellitus. Greenspan’s Basic & Clinical Endocrinology, The McGraw-Hill. [9th ed.]. Available online: https://accessmedicine.mhmedical.com/content.aspx?bookid=380§ionid=39744057.

5. Diabetes (2024, May 11). World Health Organization. Available online: https://www.who.int/news-room/fact-sheets/detail/diabetes.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3