Diverse Methods with Stereoselective Induction in the Asymmetric Biginelli Reaction-Reference-Cited by-同舟云学术

Diverse Methods with Stereoselective Induction in the Asymmetric Biginelli Reaction

Published:2024-08-15 Issue:16 Volume:29 Page:3864
ISSN:1420-3049
Container-title:Molecules
language:en
Short-container-title:Molecules

Author:

Díaz-Fernández Marcos¹²^ORCID,Algarra Manuel³^ORCID,Calvo-Losada Saturnino²^ORCID,Quirante José-Joaquín²^ORCID,Sarabia Francisco¹^ORCID,Pino-González María-Soledad¹^ORCID

Affiliation:

1. Department of Organic Chemistry, Faculty of Sciences, University of Málaga, 29071 Málaga, Spain

2. Department of Physical Chemistry, Faculty of Sciences, University of Málaga, 29071 Málaga, Spain

3. Department of Science, INAMAT2-Institute for Advanced Materials and Mathematics, Public University of Navarra, 31006 Pamplona, Spain

Abstract

The relevance of the asymmetric Biginelli reaction (ABR) has been increased in this century, due to the pharmacological application of its products. This review focuses predominantly on articles published in the period from 2015 to 2024 on asymmetric synthetic advances in the formation of dihydropyrimidinones (DHPMs), dihydropyrimidinethiones (DHPMTs), and related compounds. The relevant bibliography on general processes in the Biginelli reaction and some methods of separation of isomers have also been referenced.

Funder

Ministry of Science and Innovation

Publisher

MDPI AG

Link

https://www.mdpi.com/1420-3049/29/16/3864/pdf

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