Role of Endoscopic Techniques in the Diagnosis of Complications of Allogeneic Hematopoietic Stem Cell Transplantation: A Review of the Literature
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Published:2024-07-25
Issue:15
Volume:13
Page:4343
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ISSN:2077-0383
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Container-title:Journal of Clinical Medicine
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language:en
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Short-container-title:JCM
Author:
Bangolo Ayrton1ORCID, Dey Shraboni1ORCID, Nagesh Vignesh Krishnan1ORCID, Gumer Kabir1, Avetisyan Lida1, Islam Saima1, Sahotra Monika1, Millett Melissa1, Alqinai Budoor1, Pender Silvanna1, Dunraj Yazmika1, Syeda Habiba1, Tasneem Beegum1, Duran Mikel1, Deugd Nicoleta De1, Thakur Prasad1, Weissman Simcha1, Cho Christina2
Affiliation:
1. Department of Internal Medicine, HMH Palisades Medical Center, North Bergen, NJ 07047, USA 2. Division of Bone Marrow Transplant and Cellular Therapy, John Theurer Cancer Center, Hackensack, NJ 07601, USA
Abstract
Allogeneic stem cell transplantation (Allo-SCT) implies that a donor and a recipient are not genetically identical. Allo-SCT is used to cure a variety of conditions, including hematologic malignancies using the graft versus tumor effect, nonmalignant hematologic, immune deficiencies, and, more recently, genetic disorders and inborn errors of metabolism. Given the immunosuppressive and myeloablative nature of some of the conditioning chemotherapy regimens used during the Allo-SCT, patients are often at high risk of infection, including viral infections affecting the gastrointestinal tract, following the transplant. Furthermore, other complications such as hepatic sinusoidal obstruction syndrome (SOS) or graft-versus-host disease may occur post-transplant and may require endoscopy to assist in the diagnosis. This review will provide newer insights into the importance of endoscopic techniques in the diagnosis of post-Allo-SCT complications with a focus on safety and timing.
Reference88 articles.
1. Kaushansky, K., Prchal, J.T., Burns, L.J., Lichtman, M.A., Levi, M., and Linch, D.C. (2021). Hematopoietic Stem Cell Transplantation. Williams Hematology, McGraw-Hill Education. [10th ed.]. 2. Loscalzo, J., Fauci, A., Kasper, D., Hauser, S., Longo, D., and Jameson, J.L. (2022). Hematopoietic Cell Transplantation. Harrison’s Principles of Internal Medicine, McGraw-Hill Education. [21st ed.]. 3. National Institutes of Health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: I. Diagnosis and staging working group report;Filipovich;Biol. Blood Marrow Transplant.,2005 4. Assessing the yield and safety of endoscopy in acute graft-vs-host disease after hematopoietic stem cell transplant;Rajan;World J. Gastrointest. Endosc.,2020 5. Acyclovir for prevention of cytomegalovirus infection and disease after allogeneic marrow transplantation;Meyers;N. Engl. J. Med.,1988
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