Affiliation:
1. Department of Ophthalmology, Shimane University Faculty of Medicine, Izumo 693-8501, Japan
Abstract
(1) Background: In glaucoma patients, it is observed that intraocular pressure (IOP) in non-surgical eyes decreases during hospitalization, but detailed data have not been reported. This study aimed to examine changes in IOP in the non-surgical eyes of patients admitted for glaucoma surgery. (2) Methods: This retrospective study included 487 patients (254 males, 233 females). Statistical analysis was performed separately for groups that were and were not under medication treatment. (3) Results: In non-surgical eyes, the difference in IOP between admission and discharge was −1.6 ± 4.8 mmHg (95% confidence interval (CI), −2.1 to −1.2; p < 0.0001) with a significant decrease in the medication group (n = 414), while it was −0.6 ± 4.8 mmHg with no significant change observed (95% confidence interval (CI), −1.7 to 0.57; p = 0.33) in the non-medication group (n = 73). Multiple regression analysis of the medication group showed that IOP at admission (p < 0.0001) and older age (p = 0.03) were associated with the reduction or the rate of reduction in IOP. (4) Conclusions: IOP in the non-surgical eyes of patients admitted for glaucoma surgery with medication decreased during hospitalization. The reduction was more pronounced in individuals with higher IOP at admission and in older patients. It is possible that improved medication adherence contributes to the lowering of IOP.
Reference25 articles.
1. Glaucoma: Now and beyond;Jayaram;Lancet,2023
2. Proportion of Glaucoma Types and Surgeries Among Young, Pre-Old, Old, and Oldest-Old Age Groups or Different Sex Groups;Tanito;Clin. Ophthalmol.,2022
3. Global prevalence of glaucoma and projections of glaucoma burden through 2040: A systematic review and meta-analysis;Tham;Ophthalmology,2014
4. Glaucoma in Adults-Screening, Diagnosis, and Management: A Review;Stein;Jama,2021
5. Nanotechnology for Medical and Surgical Glaucoma Therapy—A Review;Occhiutto;Adv. Ther.,2020