Gold Nanoclusters Synthesized within Single-Chain Nanoparticles as Catalytic Nanoreactors in Water

Author:

Pinacho-Olaciregui Jokin12ORCID,Verde-Sesto Ester13,Taton Daniel2ORCID,Pomposo José A.134ORCID

Affiliation:

1. Centro de Física de Materiales (CSIC–UPV/EHU)–Materials Physics Center MPC, Pº Manuel Lardizabal 5, E-20018 Donostia, Spain

2. Laboratoire de Chimie des Polymères Organiques (LCPO), Université de Bordeaux INP–ENSCBP, 16 av. Pey Berland, 33607 Pessac CEDEX, France

3. IKERBASQUE–Basque Foundation for Science, Plaza Euskadi 5, E-48009 Bilbao, Spain

4. Departamento de Polímeros y Materiales Avanzados, Física, Química y Tecnología, University of the Basque Country (UPV/EHU), Pº Manuel Lardizabal 3, E-20800 Donostia, Spain

Abstract

Metalloenzymes are able to catalyze complex biochemical reactions in cellular (aqueous) media with high efficiency. In recent years, a variety of metal-containing single-chain nanoparticles (SCNPs) have been synthesized as simplified metalloenzyme-mimetic nano-objects. However, most of the metal-containing SCNPs reported so far contained complexed metal ions but not metal nanoclusters (NCs) with diameter <5 nm, which could be used as powerful, emerging catalysts. Herein, we report the synthesis of gold nanoclusters (Au-NCs) within SCNPs and the further use of Au-NCs/SCNPs as catalytic nanoreactors in water. We demonstrate that a common motif contained in several drugs (i.e., the aminophenyl–oxazolidinone fragment present in Rivaroxaban, Sutezolid, and Linezolid) can be efficiently prepared in water from a hydrophobic precursor compound by using the Au-NCs/SCNPs as efficient catalytic nanoreactors. In summary, this work paves the way forthe synthesis of metal–NCs/SCNPs for advanced catalysis in aqueous media.

Publisher

MDPI AG

Reference30 articles.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3