Abstract
In the present study, the simulation of an immunotherapy effect for a known dynamical system, that describes the process for avascular, vascular, and metastasis tumor growth based on a chemical network model, has been presented. To this end, square signals of various amplitudes have been used, to model the effect of external therapy control, in order to affect the population of immune cells. The results of the simulations show that for certain values of the amplitude of the square signal, the populations of the proliferating tumor cells in the vascular and metastasis stages have been reduced.
Reference44 articles.
1. A Review of Mathematical Models of Cancer–Immune Interactions in the Context of Tumor Dormancy;Wilkie,2013
2. Hallmarks of Cancer: The Next Generation
3. Fractal Analysis in a Systems Biology Approach to Cancer;Bizzarri,2011
4. Mathematical models of cancer dormancy
5. The Universal Dynamics of Tumor Growth
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献