Relationship between Thought Style, Emotional Response, Post-Traumatic Growth (PTG), and Biomarkers in Cancer Patients-Reference-Cited by-同舟云学术

Relationship between Thought Style, Emotional Response, Post-Traumatic Growth (PTG), and Biomarkers in Cancer Patients

Published:2024-06-13 Issue:6 Volume:21 Page:763
ISSN:1660-4601
Container-title:International Journal of Environmental Research and Public Health
language:en
Short-container-title:IJERPH

Author:

Sierra-Murguía Mariana¹^ORCID,Guevara-Sanginés Martha L.²,Navarro-Contreras Gabriela³^ORCID,Peralta-Castillo Guillermo¹,Padilla-Rico Amalia¹,González-Alcocer Lucía¹,Padrós-Blázquez Ferrán⁴

Affiliation:

1. Cancer Center Tec100, Ignacio Zaragoza 263 H16, Col. Centro, Querétaro 76000, QE, Mexico

2. Economic Administrative Science Division, University of Guanajuato, Fraccionamiento 1, Col. El Establo S/N, Guanajuato 36250, GJ, Mexico

3. Health Science Division, University of Guanajuato, Blvd. Puente Milenio #1001, Fracción del Predio San Carlos, León 37670, GJ, Mexico

4. Psychology Faculty, Universidad Michoacana San Nicolás de Hidalgo, Francisco Villa 450, Col. Dr. Miguel Silva, Morelia 58120, MC, Mexico

Abstract

(1) Introduction: Cancer diagnosis has been related to depression, anxiety, and distress, as well as to post-traumatic growth (PTG). One of the mediating variables for emotional response is thought style (rumination, cognitive avoidance, and cognitive engagement). (2) Aim: To identify the relationship between thought style and emotional responses to cancer. A secondary aim was to identify the relationship between emotional responses and inflammatory immunological biomarkers. (3) Method: A total of 115 patients with cancer were included in the study. Before initiating cancer treatment, patients were assessed using the Hospital Anxiety and Depression Scale (HADS), distress thermometer, and Post-Traumatic Growth Inventory (PTGI). Patients provided their most recent blood biometry. (4) Results: Rumination correlated with anxiety, depression, and distress. Cognitive avoidance correlated with PTG (−0.240) and distress (−0.209). Cognitive engagement correlated with PTG (0.393). Regarding thought style and biomarkers, a negative correlation was observed for absolute neutrophils with cognitive avoidance (−0.271) and rumination (0.305). Regarding biomarkers and emotional responses, there was a negative correlation between PTG and absolute lymphocytes (−0.291). There was also a correlation between PTG and neutrophils (0.357) and neutrophil-to-lymphocyte ratio (NLR) (0.295). (5) Conclusions: Thought style is related to the emotional response to a cancer diagnosis; rumination is related to depression, distress, and anxiety; and cognitive engagement is related to PTG. PTG is related to inflammation and immunological biomarkers.

Funder

CONAHCYT

Publisher

MDPI AG

Link

https://www.mdpi.com/1660-4601/21/6/763/pdf

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