Characterizing Multimorbidity Prevalence and Adverse Outcomes in Ethnically and Culturally Diverse Sub-Populations in India: Gaps, Opportunities, and Future Directions

Author:

Zanwar Preeti Pushpalata1234ORCID,Taylor Robyn5,Hill-Jarrett Tanisha G.67,Tsoy Elena67,Flatt Jason D.8ORCID,Mirza Zunera5,Hill Carl V.9,Perianayagam Arokiasamy10ORCID

Affiliation:

1. Jefferson College of Population Health, Thomas Jefferson University, Philadelphia, PA 19107, USA

2. Irma Lerma Rangel College of Pharmacy, Texas A&M University, Kingsville, TX 78363, USA

3. Jie Du Center for Innovation and Excellence for Drug Development, University of Pacific, Stockton, CA 95211, USA

4. The National Institutes on Aging (NIA) Funded Network on Education, Biosocial Pathways, and Dementia in Diverse Populations (EBDDP), College Park, MD 20742, USA

5. National Association of Chronic Disease Directors, Decatur, GA 30030, USA

6. Memory and Aging Center, University of California, San Francisco, CA 94143, USA

7. Global Brain Health Institute, University of California San Francisco & Trinity College Dublin, San Francisco, CA 94158, USA

8. School of Public Health, University of Nevada, Las Vegas, NV 89119, USA

9. Alzheimer’s Association, Chicago, IL 60601, USA

10. Social and Economic Survey Research Institute, Qatar University, Doha P.O. Box 2713, Qatar

Abstract

India is a large middle-income country and has surpassed China in overall population, comprising 20% of the global population (over 1.43 billion people). India is experiencing a major demographic shift in its aging population. Chronic diseases are common among older adults and can be persistent over the life course, lead to the onset of disability, and be costly. Among older adults in India, the existence of multiple comorbid chronic conditions (i.e., multimorbidity) is rapidly growing and represents a burgeoning public health burden. Prior research identified greater rates of multimorbidity (e.g., overweight/obesity diabetes, hypertension, cardiovascular disease, stroke, and malignancies) in minority populations in the United States (U.S.); however, limited studies have attempted to characterize multimorbidity among older adult sub-populations residing in India. To address this gap, we conducted a narrative review of studies on multimorbidity using the data from the Longitudinal Aging Study of India (LASI), the largest nationally representative longitudinal survey study of adults in India. Our definition of multimorbidity was the presence of more than two conditions in the same person. Our findings, based on 15 reviewed studies, aim to (1) characterize the definition and measurement of multimorbidity and to ascertain its prevalence in ethnically and culturally diverse sub-populations in India; (2) identify adverse outcomes associated with multimorbidity in the Indian adult population; and (3) identify gaps, opportunities, and future directions.

Publisher

MDPI AG

Reference43 articles.

1. UN DESA Policy (2024, February 06). Brief No. 153. India Overtakes China as the World’s Most Populous Country. Available online: https://www.un.org/development/desa/dpad/publication/un-desa-policy-brief-no-153-india-overtakes-china-as-the-worlds-most-populous-country/#:~:text=In%20April%202023%2C%20India’s%20population,to%20grow%20for%20several%20decades.

2. (2024, February 06). India Ageing Report 2023. United Nations Population Fund (UNFPA). Available online: https://india.unfpa.org/sites/default/files/pub-pdf/20230926_india_ageing_report_2023_web_version_.pdf.

3. Arokiasamy, P., Uttamacharya, U., Jain, K., Biritwum, R.B., Yawson, A.E., Wu, F., Guo, Y., Maximova, T., Espinoza, B.M., and Rodríguez, A.S. (2015). The impact of multimorbidity on adult physical and mental health in low- and middle-income countries: What does the study on global ageing and adult health (SAGE) reveal?. BMC Med., 13.

4. National Center for Chronic Disease Prevention (NCCDPHP) (2024, February 06). Centers for Disease Control and Prevention, Available online: https://www.cdc.gov/chronicdisease/index.htm.

5. Ministry of Health and Family Welfare (2024, February 06). Government of India, Available online: https://www.mohfw.gov.in/.

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