One-Year Survival after Cardiac Surgery in Frail Older People—Social Support Matters: A Prospective Cohort Study

Author:

Castro Maria de Lurdes1ORCID,Alves Marta23ORCID,Papoila Ana Luisa23,Botelho Amália4ORCID,Fragata José5

Affiliation:

1. Anesthesiology Department, Hospital de Santa Marta, Centro Hospitalar Universitário Lisboa Central, Rua de Santa Marta, 50, 1169-024 Lisbon, Portugal

2. Epidemiology and Statistics Unit, Research Centre, Centro Hospitalar Universitário Lisboa Central, Rua Jacinta Marto, 1169-045 Lisbon, Portugal

3. Centre of Statistics and Its Applications (CEAUL), Faculty of Sciences, University of Lisbon, 1749-016 Lisbon, Portugal

4. Independent Researcher, Lisbon 1400, Portugal

5. Cardiothoracic University Clinic and Department, Hospital de Santa Marta, Centro Hospitalar Universitário Lisboa Central, Rua de Santa Marta, 50, 1169-024 Lisbon, Portugal

Abstract

There are increasing rates of cardiac surgery in the elderly. Frailty, depression, and social vulnerability are frequently present in older people, and should be considered while assessing risk and providing treatment options. We aimed to analyse the impact of clinically relevant variables on survival at one year, and identify areas of future intervention. We performed a prospective cohort study at a University Hospital, with a sample of 309 elective cardiac surgery patients 65 years old and over. Their socio-demographic and clinical variables were collected. Frailty prevalence was 61.3%, while depression was absent in the majority of patients. Mortality was 1.6% and 7.8% at 30 days and 12 months, respectively. After Kaplan–Meier analysis, severe frailty (p = 0.003), severe depression (p = 0.027), pneumonia until 30 days (p = 0.014), and re-operation until 12 months (p = 0.003) significantly reduced survival, while social support increased survival (p = 0.004). In the adjusted multivariable Cox regression model, EuroSCORE II (HR = 1.27 [95% CI 1.069–1.499] p = 0.006), pneumonia until 30 days (HR = 4.19 [95% CI 1.169–15.034] p = 0.028), re-intervention until 12 months (HR = 3.14 [95% CI 1.091–9.056] p = 0.034), and social support (HR = 0.24 [95% CI 0.079–0.727] p = 0.012) explained time until death. Regular screening for social support, depression, and frailty adds relevant information regarding risk stratification, perioperative interventions, and decision-making in older people considered for cardiac surgery.

Publisher

MDPI AG

Subject

General Medicine

Reference40 articles.

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2. National Adult Cardiac Surgery Audit (NACSA) (2023, May 28). 2021 Summary Report. Available online: https://www.nicor.org.uk/wp-content/uploads/2021/10/NACSA-Domain-Report_2021_FINAL.pdf.

3. National Adult Cardiac Surgery Audit (NACSA) (2023, May 28). 2022 Summary Report. Available online: https://www.nicor.org.uk/wp-content/uploads/2022/06/NACSA_2022-FINAL.pdf.

4. Cardiac Surgery 2021 reviewed;Doenst;Thorac. Cardiovasc. Surg.,2022

5. Frailty Assessment in the cardiovascular care of older patients;Afilalo;JACC,2014

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