The Challenge of a Recall Program from a Community-Based Hepatitis C Screening Campaign: The Effectiveness in HCV Microelimination

Author:

Chien Cheng-Hung12,Chou Tien-Shin13,Chen Li-Wei12,Lin Chih-Lang12,Chang Jia-Jang3,Liu Ching-Jung3,Chen Shuo-Wei3,Hu Ching-Chih13,Chien Rong-Nan4

Affiliation:

1. Liver Research Unit, Chang Gung Memorial Hospital, Keelung 204, Taiwan

2. Community Medicine Research Center, Chang Gung Memorial Hospital, Keelung 204, Taiwan

3. Division of Gastroenterology, Chang Gung Memorial Hospital, Keelung 204, Taiwan

4. Liver Research Unit, Linkou Chang Gung Memorial Hospital and University College of Medicine, Taoyuan 333, Taiwan

Abstract

The optimal strategy for the microelimination of HCV within community settings remains ambiguous. We evaluated the percentage of participants who achieved linkage to care (LTC) following the conclusion of a screening campaign and examined the diverse factors influencing LTC among these individuals. The effectiveness of recall intervention for the non-LTC population and its barriers were analyzed. We initiated an HCV patient recall program to identify HCV participants who might not be treated after the HCV screening campaign. The program staff recalled HCV participants who were lost to follow-up via telephone from March 2019 to June 2019. They were informed of HCV treatment’s importance, efficacy, availability, and safety. Among 185 participants infected with HCV, 109 (58.9%) obtained LTC. Compared with those who had LTC, those without LTC were older, had lower education levels, were less aware of their HCV infection, less frequently lived in urban areas, and had less health insurance. At the end of the recall program, 125 (67.6%) persons had linkage to care. The proportion of LTC increased by 8.7%. In total, 119 persons had an HCV RNA test, and 82 (68.9%) had viremia. Of the 82 patients with viremia, 78 (95.1%) received antiviral therapy, and 76 (97.4%) achieved a sustained virological response. After a community screening campaign, 59% of participants with anti-HCV-positive tests had LTC. The recall program increased this by 9%. However, 32% of HCV participants still could not be linked to care. Outreach care for non-LTC patients is a method worth trying in order to achieve the microelimination of HCV in rural communities.

Funder

Chang Gung Memorial Hospital

Publisher

MDPI AG

Reference23 articles.

1. WHO (2017). Global Hepatitis Report, World Health Organization.

2. WHO (2021). Interim Guidance for Country Validation of Viral Hepatitis Elimination, World Health Organization.

3. Treading lightly: Finding the best way to use public health surveillance of hepatitis C diagnoses to increase access to cure;Stoove;Int. J. Drug Policy,2020

4. Taiwan accelerates its efforts to eliminate hepatitis C;Chien;Glob. Health Med.,2021

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