Surveillance of Avian Metapneumovirus in Non-Vaccinated Chickens and Co-Infection with Avian Pathogenic Escherichia coli
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Published:2023-12-28
Issue:1
Volume:12
Page:56
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ISSN:2076-2607
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Container-title:Microorganisms
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language:en
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Short-container-title:Microorganisms
Author:
Salles Gleidson Biasi Carvalho12, Pilati Giulia Von Tönnemann1ORCID, Savi Beatriz Pereira1, Muniz Eduardo Correa2, Dahmer Mariane1, Vogt Josias Rodrigo2, de Lima Neto Antonio José2, Fongaro Gislaine1ORCID
Affiliation:
1. Laboratory of Applied Virology, Department of Microbiology, Immunology and Parasitology, Universidade Federal de Santa Catarina, Florianópolis 88040-900, SC, Brazil 2. Zoetis Industry of Veterinary Products LTDA, São Paulo 04709-11, SP, Brazil
Abstract
Brazil is the second largest producer of broiler chicken in the world, and the surveillance of avian pathogens is of great importance for the global economy and nutrition. Avian metapneumovirus (aMPV) infection results in high rates of animal carcass losses due to aerosacculitis and these impacts can be worsened through co-infection with pathogenic bacteria, particularly Escherichia coli (APEC). The present study evaluated the seroprevalence of the main aMPV subtypes in unvaccinated broiler chickens from poultry farms in Brazil, as well as the clinical effects of co-infection with APEC. Blood samples, respiratory swabs, femurs, liver, and spleen of post-mortem broiler chickens were collected from 100 poultry production batches, totaling 1000 samples. The selection of the production batch was based on the history of systemic and respiratory clinical signs. The results indicated that 20% of the lots showed serological evidence of the presence of aMPV, with two lots being positive for aMPV-B. A total of 45% of batches demonstrated co-infection between aMPV and APEC. The results point to the need for viral surveillance, targeted vaccination, and vaccination programs, which could reduce clinical problems and consequently reduce the use of antibiotics to treat bacterial co-infections.
Funder
Santa Catarina Research Foundation CAPES CNPq UFSC Santa Catarina Research Foundation (Fundação de Amparo à Pesquisa e Inovação of Santa Catarina, FAPESC, Santa Catarina, Brazil), Federal University of Santa Catarina (UFSC) Project SIGPEX
Subject
Virology,Microbiology (medical),Microbiology
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