Early Detection of the Recombinant SARS-CoV-2 XAN Variant in Bulgaria: Initial Genomic Insights into Yet Another Piece of the Growing Puzzle of Recombinant Clades-Reference-Cited by-同舟云学术

Early Detection of the Recombinant SARS-CoV-2 XAN Variant in Bulgaria: Initial Genomic Insights into Yet Another Piece of the Growing Puzzle of Recombinant Clades

Published:2023-08-09 Issue:8 Volume:11 Page:2041
ISSN:2076-2607
Container-title:Microorganisms
language:en
Short-container-title:Microorganisms

Author:

Alexiev Ivailo¹^ORCID,Ivanov Ivan¹^ORCID,Giovanetti Marta²³^ORCID,Cella Eleonora⁴^ORCID,Stoikov Ivan¹^ORCID,Donchev Deyan¹^ORCID,Grigorova Lyubomira¹,Gancheva Anna¹,Dimitrova Reneta¹^ORCID,Scarpa Fabio⁵^ORCID,Korsun Neli¹^ORCID,Trifonova Ivelina¹^ORCID,Dobrinov Veselin¹,Kantardjiev Todor¹,Christova Iva¹,Ciccozzi Massimo⁶^ORCID

Affiliation:

1. National Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria

2. Instituto Rene Rachou Fundação Oswaldo Cruz, Belo Horizonte 30190-009, Minas Gerais, Brazil

3. Sciences and Technologies for Sustainable Development and One Health, Università Campus Bio-Medico di Roma, 00128 Rome, Italy

4. Burnett School of Biomedical Sciences, University of Central Florida, Orlando, FL 32816, USA

5. Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy

6. Unit of Medical Statistics and Molecular Epidemiology, Università Campus Bio-Medico di Roma, 00128 Rome, Italy

Abstract

The first recombinant SARS-CoV-2 variants were identified in 2022, causing public health concerns. The importance of recombinant variants has increased especially since the WHO designated the recombinant variant XBB and its lineages as subvariants that require monitoring on 20 November 2022. In this study, we provide the first insights into the new SARS-CoV-2 variant named XAN, a recombinant composed of Omicron sub-lineages BA.2 and BA.5. To our knowledge, this is the first report on the recombinant SARS-CoV-2 XAN variant identified in Bulgaria.

Publisher

MDPI AG

Subject

Virology,Microbiology (medical),Microbiology

Link

https://www.mdpi.com/2076-2607/11/8/2041/pdf

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