Abstract
Life-threatening bacterial infections have been well-controlled by antibiotic therapies and this approach has greatly improved the health and lifespan of human beings. However, the rapid and worldwide emergence of multidrug resistant (MDR) bacteria has forced researchers to find alternative treatments for MDR infections as MDR bacteria can sometimes resist all the present day antibiotic therapies. In this respect, nanomaterials have emerged as innovative antimicrobial agents that can be a potential solution against MDR bacteria. The present review discusses the advantages of nanomaterials as potential medical means and carriers of antibacterial activity, the types of nanomaterials used for antibacterial agents, strategies to tackle toxicity of nanomaterials for clinical applications, and limitations which need extensive studies to overcome. The current progress of using different types of nanomaterials, including new emerging strategies for the single purpose of combating bacterial infections, is also discussed in detail.
Funder
Pusan National University
National Research Foundation of Korea
Subject
Virology,Microbiology (medical),Microbiology
Reference165 articles.
1. Antibiotic resistance: What is so special about multidrug-resistant Gram-negative bacteria?;Exner;GMS Hyg. Infect Control.,2017
2. Tackling Drug-Resistant Infections Globally: Final Report and Recommendations, The Review on Antimicrobial Resistance
https://amr-review.org/sites/default/files/160525_Final%20paper_with%20cover.pdf
3. Combatting antibiotic-resistant bacteria using nanomaterials
4. WHO Publishes List of Bacteria for Which New Antibiotics Are Urgently Needed
https://www.who.int/news-room/detail/27-02-2017-who-publishes-list-of-bacteria-for-which-new-antibiotics-are-urgently-needed
5. Bacteria antibiotic resistance: New challenges and opportunities for implant-associated orthopedic infections
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