Application of Flow Cytometry in the Diagnosis of Bovine Epidemic Disease

Author:

Liu Zhilin1ORCID,Zhang Yuliang2,Zhao Donghui2,Chen Yunjiao1,Meng Qinglei1ORCID,Zhang Xin1,Jia Zelin1,Cui Jiayu1,Wang Xueli1ORCID

Affiliation:

1. College of Animal Science and Technology, Inner Mongolia Minzu University, Tongliao 028000, China

2. Tongliao City Animal Quarantine Technical Service Centre, Tongliao 028000, China

Abstract

As science and technology continue to advance, the use of flow cytometry is becoming more widespread. It can provide important information about cells in the body by detecting and analysing them, thereby providing a reliable basis for disease diagnosis. In the diagnosis of bovine epidemic diseases, flow cytometry can be used to detect bovine viral diarrhoea, bovine leukaemia, bovine brucellosis, bovine tuberculosis, and other diseases. This paper describes the structure of a flow cytometer (liquid flow system, optical detection system, data storage and analysis system) and its working principles for rapid quantitative analysis and sorting of single cells or biological particles. Additionally, the research progress of flow cytometry in the diagnosis of bovine epidemic diseases was reviewed in order to provide a reference for future research and application of flow cytometry in the diagnosis of bovine epidemic diseases.

Funder

The Inner Mongolia Natural Science Foundation

Publisher

MDPI AG

Subject

Virology,Infectious Diseases

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