Sustaining the Elimination of Measles, Rubella and Congenital Rubella Syndrome in the Americas, 2019–2023: From Challenges to Opportunities

Author:

Rey-Benito Gloria1ORCID,Pastor Desirée1,Whittembury Alvaro1ORCID,Durón Regina1,Pacis-Tirso Carmelita1,Bravo-Alcántara Pamela1,Ortiz Claudia1,Andrus Jon2

Affiliation:

1. Comprehensive Immunization Program, Pan American Health Organization, 525 23rd Street, NW, Washington, DC 20037, USA

2. Department of Global Health, Milken Institute School of Public Health, George Washington University, Washington, DC 20037, USA

Abstract

This report reviews national data from all Member States on measles, rubella, and congenital rubella syndrome (CRS) elimination in the Region of the Americas during 2019–2023. It includes an analysis of compliance with vaccination coverage, surveillance indicators, and measles outbreaks, as well as an analysis of the response capacity of the laboratory network and a country case study that meets all indicators. The sources of information were the integrated epidemiological surveillance system for measles and rubella of the Pan American Health Organization (PAHO)/World Health Organization (WHO) and the Joint Reporting Form (eJRF), among others. From 2020 to 2022, regional coverage with first (MMR-1) and second doses (MMR-2) decreased to rates below 90%. The regional suspected case notification rate was maintained above the minimum expected 2.0 suspect cases per 100,000 population, except in 2021. During 2019 to 2023, 18 countries experienced outbreaks, with two of the outbreaks resulting in re-established endemic transmission. In conclusion, two countries in the Americas have not maintained measles elimination, but by the end of 2023 no country showed endemic measles transmission. One of the countries that lost its certification of elimination in 2018 managed to be reverified in 2023; the other is pending reverification. All countries maintained rubella elimination. Despite these challenges, the sustainability of the elimination of these diseases remains a health priority in the Region.

Funder

PAHO

Publisher

MDPI AG

Reference23 articles.

1. Pan American Health Organization (1994, January 26–30). Elimination of Measles in the Americas. Proceedings of the XXIV Meeting of the Pan American Sanitary Conference, Washington, DC, USA. Available online: https://iris.paho.org/bitstream/handle/10665.2/57514/CSP24-res_eng.pdf?sequence=1&isAllowed=y.

2. The Americas: Paving the Road Toward Global Measles Eradication;Castillo;J. Infect. Dis.,2011

3. Pan American Health Organization (2024, April 30). Plan of Action for Documentation and Verification of Measles, Rubella and Congenital Rubella Syndrome in the Region of the Americas. Available online: https://www3.paho.org/hq/dmdocuments/2012/PoA-Documentation-Verification-MRCRS-Elimination-s.pdf.

4. Pan American Health Organization (2016, January 26–30). CD55/DIV/09 Special Report on Diverse Documents Remarks by Dr. Merceline Dahl-Regis President of the International Expert Committee for the Verification of Measles and Rubella Elimination. 55 Directing Council. Proceedings of the 68th Session of the Regional of the World Health Organization, Washington, DC, USA. Available online: https://www3.paho.org/hq/dmdocuments/2016/CD55-DIV-9-s.pdf.

5. Pan American Health Organization (2017, January 25–29). Resolution CSP29/8. Plan of Action for the Sustainability of Measles, Rubella, and Congenital Rubella Syndrome Elimination in the Americas 2018–2023. Proceedings of the 29th Pan American Sanitary Conference at the 69th Session of the Regional Committee of the Americas, Washington, DC, USA. Available online: https://www3.paho.org/hq/index.php?option=com_docman&view=download&category_slug=29-en-9249&alias=41210-csp29-8-e-210&Itemid=270&lang=en.

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