The Urgent Need for Dengue Vaccination: Combating an Escalating Public Health Crisis in Pakistan

Author:

Iqtadar Somia1234ORCID,Akram Javed3,Khan Amjad35ORCID

Affiliation:

1. Dengue Expert Advisory Group, Lahore 54000, Pakistan

2. Department of Medicine, King Edward Medical University, Lahore 54000, Pakistan

3. Pakistan Society of Internal Medicine (PSIM), Lahore 54000, Pakistan

4. Asia Dengue Voice & Action Next Generation (ADVA NexGen) Group, 8 Fleming Road, Wanchai, Hong Kong, China

5. Department of Oncology, University of Oxford, Oxford OX3 7DQ, UK

Abstract

Dengue fever, caused by the dengue virus (DENV), poses a significant global health threat, with a dramatic increase in cases driven by climate change, urbanization, and mosquito resistance. In Pakistan, a country with a population of 240 million, the world’s fifth largest, dengue has emerged as an escalating public health crisis, with seasonal outbreaks severely straining the healthcare system. Despite decades of vector control efforts, there has not been much success, necessitating the introduction of dengue vaccination to boost population immunity. Recent advancements in vaccine development demonstrate promising efficacy and safety profiles, even in dengue-naive individuals. Implementing a dengue vaccination program in Pakistan could significantly reduce the disease burden, lower healthcare costs, and prevent future outbreaks. Integrating vaccination with existing public health initiatives can achieve high coverage and improve overall public health outcomes.

Publisher

MDPI AG

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5. Climate change and the increased burden of dengue fever in Pakistan;Abid;Lancet Infect. Dis.,2023

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