Simultaneous Multiple-Stages Mpox Genital Lesions on the Same Site in a Traveler to Greece: A Case Report

Author:

Tagka Anna1,Geronikolou Styliani2ORCID,Evaggelopoulos Apostolos1,Grigoropoulou Sotiria3,Kavatha Dimitra3,Botsi Chryssoula1,Papadopoulou Aggeliki1,Tryfinopoulou Kyriaki4ORCID,Katsoulidou Antigoni4,Pappa Styliani5,Papa Anna5ORCID,Paparizos Vasilios1,Nicolaidou Electra1ORCID,Tsiodras Sotirios3ORCID,Stratigos Alexandros J.1

Affiliation:

1. 1st Department of Dermatology and Venereology, Athens Medical School, “Andreas Syggros” Hospital for Skin and Venereal Diseases, National and Kapodistrian University, 15772 Athens, Greece

2. Clinical Translational and Experimental Surgery Center, Biomedical Research Foundation of the Academy of Athens, 11527 Athens, Greece

3. 4th Department of Internal Medicine, Athens Medical School, National and Kapodistrian University, 11527 Athens, Greece

4. Central Public Health Laboratory, National Public Health Organization, 15123 Athens, Greece

5. Department of Microbiology, Medical School, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece

Abstract

A 47-year-old Caucasian traveller from an mpox (formerly monkeypox and also best suited abbreviated MPX)-endemic country was referred for a skin rash, of recent onset, confined to the genital area. The rash consisted of erythematous umbilicated papules, vesicles and pustules with a characteristic white ring. The lesions were observed simultaneously at different stages of progression on the same anatomical site, a clinical presentation that is not encountered frequently. The patient was febrile, fatigued and had blood-tinged cough. The clinical suspicion of mpox was raised, and the initial real-time PCR identified a non-variola orthopox virus, which was confirmed at the National Reference Laboratory to belong to the West African clade.

Publisher

MDPI AG

Subject

Pharmacology (medical),Infectious Diseases,Drug Discovery,Pharmacology,Immunology

Reference41 articles.

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2. Human monkeypox;McCollum;Clin. Infect. Dis.,2014

3. Emergence of Monkeypox—West and Central Africa, 1970–2017;Durski;MMWR Morb. Mortal. Wkly. Rep.,2018

4. WHO (2022, January 01). Second Meeting of the International Health Regulations (2005) (IHR) Emergency Committee Regarding the Multi-country Outbreak of Monkeypox. 23 July 2022. Available online: https://www.who.int/news/item/23-07-2022-second-meeting-of-the-international-health-regulations-(2005)-(ihr)-emergency-committee-regarding-the-multi-country-outbreak-of-monkeypox.

5. (2022, January 01). ECDC. Available online: https://www.who.int/europe/news/item/14-04-2023-who-ecdc-report--antimicrobial-resistance-threatens-patient-safety-in-european-region.

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