Approaches for Selective Vaccinations in Cirrhotic Patients

Author:

Casella Giovanni1ORCID,Ingravalle Fabio2ORCID,Ingravalle Adriana3,Andreotti Stefano4,Bonetti Fulvio5,Monti Claudio5,Falbo Rosanna6,Rumi Maria Grazia7

Affiliation:

1. General Practitioner Limbiate, 20812 Limbiate, Italy

2. School of Specialization in Hygiene and Preventive Medicine, University of Rome Tor Vergata, 00133 Rome, Italy

3. School of Specialization in Anesthesiology and Critical Care, University of Rome Sapienza, Policlinico Umberto I, 00133 Rome, Italy

4. RSA “E.Bernardelli”, Clinica Polispecialistica San Carlo, 20037 Paderno Dugnano (Milan), Italy

5. General Practitioner ATS Lecco-Monza Barlassina, 20825 Monza Brianza, Italy

6. Clinical Pathology Department, Desio Hospital, 20832 Desio, Italy

7. Hepatology Unit “San Giuseppe-Multimedica” Hospital, University of Milan, 20123 Milan, Italy

Abstract

Bacterial and viral infections are common in cirrhotic patients, and their occurrence is associated with the severity of liver disease. Bacterial infection may increase the probability of death by 3.75 times in patients with decompensated cirrhosis, with ranges of 30% at 1 month and 63% at 1 year after infection. We illustrate the indications and the modalities for vaccinating cirrhotic patients. This topic is important for general practitioners and specialists.

Publisher

MDPI AG

Subject

Pharmacology (medical),Infectious Diseases,Drug Discovery,Pharmacology,Immunology

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