Factors Associated with Uptake of Routine Measles-Containing Vaccine Doses among Young Children, Oromia Regional State, Ethiopia, 2021

Author:

Woyessa Abyot Bekele12ORCID,Shah Monica P.3,Azmeraye Binyam Moges4,Pan Jeff5,Lisanwork Leuel4,Yimer Getnet4ORCID,Wang Shu-Hua5ORCID,Nuorti J. Pekka2,Artama Miia2,Matanock Almea M.36,An Qian3,Samuel Paulos1,Tolera Bekana1,Kenate Birhanu1ORCID,Bekele Abebe1,Deti Tesfaye1,Wako Getachew7,Shiferaw Amsalu7,Tefera Yohannes Lakew8,Kokebie Melkamu Ayalew8,Anbessie Tatek Bogale9ORCID,Wubie Habtamu Teklie10,Wallace Aaron3ORCID,Sugerman Ciara E.3

Affiliation:

1. Oromia Regional Health Bureau, Addis Ababa P.O. Box 24341, Ethiopia

2. Health Sciences Unit, Faculty of Social Sciences, Tampere University, 33100 Tampere, Finland

3. Global Immunization Division, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA

4. Global One Health Initiative, Ohio State University, Addis Ababa P.O. Box 1176, Ethiopia

5. College of Medicine, Ohio State University, Columbus, OH 43210, USA

6. Global Immunization Division, CDC-Ethiopia, Addis Ababa P.O. Box 3243, Ethiopia

7. UNICEF, Addis Ababa P.O. Box 1169, Ethiopia

8. Ministry of Health of Ethiopia, Addis Ababa P.O. Box 1234, Ethiopia

9. African Field Epidemiology Network, Addis Ababa P.O. Box 12874, Ethiopia

10. Ethiopian Public Health Institute, Addis Ababa P.O. Box 1242, Ethiopia

Abstract

Recommended vaccination at nine months of age with the measles-containing vaccine (MCV1) has been part of Ethiopia’s routine immunization program since 1980. A second dose of MCV (MCV2) was introduced in 2019 for children 15 months of age. We examined MCV1 and MCV2 coverage and the factors associated with measles vaccination status. A cross-sectional household survey was conducted among caregivers of children aged 12–35 months in selected districts of Oromia Region. Measles vaccination status was determined using home-based records, when available, or caregivers’ recall. We analyzed the association between MCV1 and MCV2 vaccination status and household, caregiver, and child factors using logistic regression. The caregivers of 1172 children aged 12–35 months were interviewed and included in the analysis. MCV1 and MCV2 coverage was 71% and 48%, respectively. The dropout rate (DOR) from the first dose of Pentavalent vaccine to MCV1 was 22% and from MCV1 to MCV2 was 46%. Caregivers were more likely to vaccinate their children with MCV if they gave birth at a health facility, believe that their child had received all recommended vaccines, and know the required number of vaccination visits and doses. MCV2 coverage was low, with a high measles dropout rate (DOR). Caregivers with high awareness of MCV and its schedule were more likely to vaccinate their children. Intensified demand generation, defaulter tracking, and vaccine-stock management should be strengthened to improve MCV uptake.

Funder

Gavi, the Vaccine Alliance

Ethiopia Targeted Country Assistance, Partner Engagement Framework

CDC-Foundation

US Centers for Disease Control and Prevention

Publisher

MDPI AG

Reference32 articles.

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4. Tamirat, K.S., and Sisay, M.M. (2019). Full immunization coverage and its associated factors among children aged 12–23 months in Ethiopia: Further analysis from the 2016 Ethiopia demographic and health survey. BMC Public Health, 19.

5. Federal Democratic Republic of Ethiopia Ministry of Health (2015). Ethiopia National Expanded Programme on Immunization Comprehensive Multi-Year Plan 2016–2020, Federal Ministry of Health.

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