Respiratory Syncytial Virus Infections in Polish Pediatric Patients from an Expert Perspective

Author:

Borszewska-Kornacka Maria K.1,Mastalerz-Migas Agnieszka2,Nitsch-Osuch Aneta3ORCID,Jackowska Teresa4ORCID,Paradowska-Stankiewicz Iwona5ORCID,Kuchar Ernest6ORCID,Mazela Jan7,Helwich Ewa8,Czech Marcin9ORCID,Lauterbach Ryszard10ORCID,Pinkas Jarosław11,Wielgoś Mirosław12,Wysocki Jacek13

Affiliation:

1. Coalition for Preemies Foundation, Medical University of Warsaw, 02-091 Warsaw, Poland

2. Department of Family Medicine, Wroclaw Medical University, 50-368 Wroclaw, Poland

3. Department of Social Medicine and Public Health, Medical University of Warsaw, 02-007 Warsaw, Poland

4. Department of Pediatrics, Centre of Postgraduate Medical Education, 01-813 Warsaw, Poland

5. Department of Epidemiology, Infectious Diseases and Surveillance, National Institute of Public Health—National Institute of Hygiene—National Research Institute, 00-791 Warsaw, Poland

6. Department of Pediatrics with Clinical Assessment Unit, Medical University of Warsaw, 02-091 Warsaw, Poland

7. Department of Neonatology, Poznan University of Medical Sciences, 60-535 Poznań, Poland

8. Institute of Mother and Child, 01-211 Warsaw, Poland

9. Polish Pharmacoeconomic Society, Institute of Mother and Child, 01-211 Warsaw, Poland

10. Polish Neonatal Society, Clinical Department, University Hospital in Krakow, 30-688 Kraków, Poland

11. Centre of Postgraduate Medical Education, 01-813 Warsaw, Poland

12. Medical Faculty, Lazarski University, 02-662 Warsaw, Poland

13. Department of Health Prevention, Faculty of Health Sciences, Poznan University of Medical Sciences, 61-701 Poznań, Poland

Abstract

Respiratory syncytial virus (RSV) is the most common pathogen causing respiratory tract infections in infants, affecting over 90% of children within the first two years of life. It may cause lower respiratory tract infections, which constitute a significant healthcare burden both in the primary and secondary care settings. Meanwhile, the data regarding RSV disease in Poland is scarce, and published data significantly differs from the numbers reported for other countries with longstanding surveillance and reporting systems. A literature review and an expert panel were conducted to (1) understand the healthcare burden of RSV infections in Poland; (2) collect data on infection seasonality, patient pathway, and management patterns; and (3) evaluate RSV infection surveillance in Poland. According to the literature, RSV is the major agent responsible for non-influenza respiratory diseases in Poland. The reported rates of hospitalization for RSV infections are 267.5/100,000 for children under 5 years of age and 1132.1/100,000 for those under 1 year of age. Comparisons with data from other countries suggest that these values may be underestimated, possibly due to insufficient access to microbiological testing and a low awareness of RSV. Infections occur mainly between December and April, however, this pattern has changed following the implementation of preventive measures for coronavirus disease 2019 in the past few years. According to available reports, bronchodilators, antibiotics, corticosteroids, and X-ray imaging have been frequently used. The surveillance system in Poland has limitations, but these may be overcome due to recent changes in healthcare law as well as the availability and reimbursement of diagnostic tests.

Funder

Coalition for Preemies Foundation

Publisher

MDPI AG

Subject

Pharmacology (medical),Infectious Diseases,Drug Discovery,Pharmacology,Immunology

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