A Qualitative Study Exploring Motivators and Barriers to COVID-19 Vaccine Uptake among Adults in South Africa and Zimbabwe

Author:

Myburgh Nellie12,Mulaudzi Mamakiri23,Tshabalala Gugulethu23,Beta Norest4,Gutu Kimberley1,Vermaak Stefanie23,Lau Charles5,Hill Catherine1ORCID,Stanberry Lawrence6ORCID,James Wilmot7,Madhi Shabir1ORCID,Makadzange Tariro4ORCID,Dietrich Janan Janine238ORCID

Affiliation:

1. Vaccines and Infectious Disease Analytics (VIDA) Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2000, South Africa

2. African Social Sciences Unit of Research and Evaluation (ASSURE), Wits Health Consortium, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2000, South Africa

3. Perinatal HIV Research Unit (PHRU), School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2000, South Africa

4. Charles River Medical Group, Harare, Zimbabwe

5. GeoPoll, 3000 Lawrence Street, Suite 125, Denver, CO 80205, USA

6. Department of Pediatrics, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA

7. Institute for Social and Economic Research and Policy, Columbia University, New York, NY 10027, USA

8. Health Systems Research Unit, South African Medical Research Council, Bellville 7538, South Africa

Abstract

While vaccines are a well-established method of controlling the spread of infectious diseases, vaccine hesitancy jeopardizes curbing the spread of COVID-19. Through the Vaccine Information Network (VIN), this study explored barriers and motivators to COVID-19 vaccine uptake. We conducted 18 focus group discussions with male and female community members, stratified by country, age group, and—for Zimbabwe only—by HIV status. Participants’ median age across both countries was 40 years (interquartile range of 22–40), and most (65.9%) were female. We conceptualized the key themes within the World Health Organization’s Strategic Advisory Group of Experts on Immunization (SAGE) 3C (convenience, confidence, complacency) vaccine hesitancy model. Barriers to vaccine uptake—lack of convenience, low confidence, and high complacency—included inaccessibility of vaccines and vaccination sites, vaccine safety and development concerns, and disbelief in COVID-19’s existence. Motivators to vaccine uptake—convenience, confidence, and low complacency—included accessibility of vaccination sites, user-friendly registration processes, trust in governments and vaccines, fear of dying from COVID-19, and knowing someone who had died from or become infected with COVID-19. Overall, vaccine hesitancy in South Africa and Zimbabwe was influenced by inconvenience, a lack of confidence, and high complacency around COVID-19 vaccines.

Funder

Schmidt Futures

Aspen Pharmacare

Bill and Melinda Gates Foundation

Consortium for Advanced Research Training in Africa

South African Medical Research Council through its Division of Research Capacity Development

South African National Treasury

CIPHER Growing

Publisher

MDPI AG

Subject

Pharmacology (medical),Infectious Diseases,Drug Discovery,Pharmacology,Immunology

Reference41 articles.

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2. World Health Organization (2023, January 16). WHO Coronavirus (COVID-19) Dashboard. Available online: https://covid19.who.int.

3. World Health Organization (2023, January 16). WHO Coronavirus (COVID-19) South Africa. Available online: https://covid19.who.int/region/afro/country/za.

4. World Health Organization (2023, January 16). WHO Coronavirus (COVID-19) Zimbabwe. Available online: https://covid19.who.int/region/afro/country/zw.

5. Dzinamarira, T., Nachipo, B., Phiri, B., and Musuka, G. (2021). COVID-19 Vaccine Roll-Out in South Africa and Zimbabwe: Urgent Need to Address Community Preparedness, Fears and Hesitancy. Vaccines, 9.

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