Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract
-
Published:2023-09-02
Issue:17
Volume:16
Page:6037
-
ISSN:1996-1944
-
Container-title:Materials
-
language:en
-
Short-container-title:Materials
Author:
Kędzierska Magdalena1, Sala Katarzyna2, Bańkosz Magdalena2, Wroniak Dominika2, Gajda Paweł3, Potemski Piotr1, Tyliszczak Bożena2ORCID
Affiliation:
1. Department of Chemotherapy, Medical University of Lodz, Copernicus Memorial Hospital of Lodz, 90-549 Lodz, Poland 2. Department of Materials Engineering, Faculty of Materials Engineering and Physics, Cracow University of Technology, 37 Jana Pawła II Av., 31-864 Krakow, Poland 3. Department of Sustainable Energy Development, Faculty of Energy and Fuels, AGH University of Science and Technology, 30 Mickiewicza Av., 30-059 Krakow, Poland
Abstract
Hydrogel materials are used in many fields of science and industry. They are of particular importance in biomedical applications. In this work, hydrogels were obtained that could act as a dressing for wounds, at the same time being a carrier of substances with antioxidant activity. The discussed materials were obtained in the field of UV radiation. The correlation between the amount of photoinitiator used and the physicochemical properties and surface morphology of the obtained materials was investigated. In addition, the hydrogels have been incorporated with wild rose extract, which is characterized by antioxidant and anti-inflammatory effects. The analysis of the sorption capacity confirmed that the obtained material is able to absorb significant amounts of incubation fluids, which, in terms of application, will enable the absorption of exudate from the wound. The highest stability of materials was noted for hydrogels obtained with the use of intermediate amounts of photoinitiator, i.e., 50 µL and 70 µL. In the case of using 20 µL or 100 µL, the photopolymerization process did not proceed properly and the obtained material was characterized by a lack of homogeneity and high brittleness. With the increase in the amount of photoinitiator, an increase in the surface roughness of hydrogel materials was confirmed. In turn, spectroscopic analysis ruled out the degradation of materials in incubation fluids, indicating the potential for their use in biomedical applications.
Subject
General Materials Science
Reference42 articles.
1. Jafar Mazumder, M.A., Sheardown, H., and Al-Ahmed, A. (2019). Synthetic Biopolymers, Springer International Publishing. 2. Current Hydrogel Advances in Physicochemical and Biological Response-Driven Biomedical Application Diversity;Cao;Signal Transduct. Target. Ther.,2021 3. V Biomedical Applications of Hydrogels: A Review of Patents and Commercial Products;Khutoryanskiy;Eur. Polym. J.,2015 4. Bashir, S., Hina, M., Iqbal, J., Rajpar, A.H., Mujtaba, M.A., Alghamdi, N.A., Wageh, S., Ramesh, K., and Ramesh, S. (2020). Fundamental Concepts of Hydrogels: Synthesis, Properties, and Their Applications. Polymers, 12. 5. Tuning Hydrogel Properties and Function Using Substituent Effects;Kohman;Soft Matter,2010
|
|