Human Health during Space Travel: State-of-the-Art Review

Author:

Krittanawong Chayakrit,Singh Nitin KumarORCID,Scheuring Richard A.,Urquieta Emmanuel,Bershad Eric M.,Macaulay Timothy R.ORCID,Kaplin ScottORCID,Dunn Carly,Kry Stephen F.ORCID,Russomano ThaisORCID,Shepanek Marc,Stowe Raymond P.,Kirkpatrick Andrew W.,Broderick Timothy J.,Sibonga Jean D.,Lee Andrew G.,Crucian Brian E.

Abstract

The field of human space travel is in the midst of a dramatic revolution. Upcoming missions are looking to push the boundaries of space travel, with plans to travel for longer distances and durations than ever before. Both the National Aeronautics and Space Administration (NASA) and several commercial space companies (e.g., Blue Origin, SpaceX, Virgin Galactic) have already started the process of preparing for long-distance, long-duration space exploration and currently plan to explore inner solar planets (e.g., Mars) by the 2030s. With the emergence of space tourism, space travel has materialized as a potential new, exciting frontier of business, hospitality, medicine, and technology in the coming years. However, current evidence regarding human health in space is very limited, particularly pertaining to short-term and long-term space travel. This review synthesizes developments across the continuum of space health including prior studies and unpublished data from NASA related to each individual organ system, and medical screening prior to space travel. We categorized the extraterrestrial environment into exogenous (e.g., space radiation and microgravity) and endogenous processes (e.g., alteration of humans’ natural circadian rhythm and mental health due to confinement, isolation, immobilization, and lack of social interaction) and their various effects on human health. The aim of this review is to explore the potential health challenges associated with space travel and how they may be overcome in order to enable new paradigms for space health, as well as the use of emerging Artificial Intelligence based (AI) technology to propel future space health research.

Publisher

MDPI AG

Subject

General Medicine

Reference289 articles.

1. (2022, November 02). The Evolving Landscape of 21st Century American Spaceflight, Available online: https://www.nasa.gov/sites/default/files/files/Emerging_Space_Report.pdf.

2. The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight;Darshi;Science,2019

3. Review and meta-analysis of epidemiological associations between low/moderate doses of ionizing radiation and circulatory disease risks, and their possible mechanisms;Little;Radiat. Environ. Biophys.,2010

4. Iron-ion radiation accelerates atherosclerosis in apolipoprotein E-deficient mice;Yu;Radiat. Res.,2011

5. Alterations in adaptive immunity persist during long-duration spaceflight;Crucian;NPJ Microgravity,2015

Cited by 12 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3