Information–Thermodynamic Method for the Study of Proliferation of Organized Cellular Structure-Reference-Cited by-同舟云学术

Information–Thermodynamic Method for the Study of Proliferation of Organized Cellular Structure

Published:2023-02-24 Issue:5 Volume:12 Page:731
ISSN:2073-4409
Container-title:Cells
language:en
Short-container-title:Cells

Author:

Volov Vyacheslav T.¹^ORCID,Volova Larisa T.¹^ORCID,Kolsanov Alexander V.¹^ORCID

Affiliation:

1. Ministry of Health of Russia, Research Institute of Biotechnology “Biotech”, Samara State Medical University, 443099 Samara, Russia

Abstract

The aim of the article was to develop an innovative method for the study of cell proliferation based on the information–thermodynamic approach, including the mathematical ratio—the entropy of cell proliferation and an algorithm for the calculation of fractal dimension of the cellular structure. Approbation of this method with pulsed electromagnetic impact on culture in vitro was implemented. It is shown on the basis of experimental data that the organized cellular structure of juvenile human fibroblasts is a fractal. The method makes it possible to determine the stability of the effect on cell proliferation. The prospects for the application of the developed method are discussed.

Publisher

MDPI AG

Subject

General Medicine

Link

https://www.mdpi.com/2073-4409/12/5/731/pdf

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