A Detection-Service-Mobile Three-Terminal Software Platform for Point-of-Care Infectious Disease Detection System

Author:

Su Xiangyi,Fang Yile,Liu Haoran,Wang Yue,Ji Minjie,Chen Zhu,Chen Hui,Li Song,Deng Yan,Jin Lian,Zhang Yuanying,Ramalingam MuruganORCID,He Nongyue

Abstract

The traditional infectious disease detection process is cumbersome, and there is only a single application scenario. In recent years, with the development of the medical industry and the impact of the epidemic situation, the number of infectious disease detection instruments based on nursing point detection has been increasing. Due to this trend, many detection instruments and massive detection data urgently need to be managed. In addition, the experiment failed due to the abnormal fluorescence curve generated by a human operator or sample impurities. Finally, the geographic information system has also played an active role in spreading and preventing infectious diseases; this paper designs a “detection-service-mobile” three-terminal system to realize the control of diagnostic instruments and the comprehensive management of data. Machine learning is used to classify the enlarged curve and calculate the cycle threshold of the positive curve; combined with a geographic information system, the detection results are marked on the mobile terminal map to realize the visual display of the positive results of nucleic acid amplification detection and the early warning of infectious diseases. In the research, applying this system to portable field pathogen detection is feasible and practical.

Funder

National Natural Science Foundation of China

Hunan Urgency Project

Publisher

MDPI AG

Subject

Clinical Biochemistry,General Medicine,Analytical Chemistry,Biotechnology,Instrumentation,Biomedical Engineering,Engineering (miscellaneous)

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