Affiliation:
1. Nutrition and Mental Health Research Group (NUTRISAM), Faculty of Medicine and Health Sciences, Universitat Rovira i Virgili (URV), 43201 Reus, Spain
2. Institut d’Investigació Sanitària Pere Virgili (IISPV), 43005 Tarragona, Spain
3. Institut d’Investigació en Atenció Primària IDIAP Jordi Gol, Institut Català de la Salut (ICS), 08007 Barcelona, Spain
4. Collaborative Group on Lifestyles, Nutrition, and Tobacco (CENIT), Institut d´Investigació en Atenció Primària IDIAP Jordi Gol, Institut Català de la Salut (ICS), 43202 Reus, Spain
Abstract
To examine the associations of sociodemographic, lifestyle, and clinical factors with cardiometabolic risk and each of its components during pregnancy in a pregnant population from Catalonia (Spain). A prospective cohort study of 265 healthy pregnant women (39 ± 5 years) in the first and third-trimesters. Sociodemographic, obstetric, anthropometric, lifestyle and dietary variables were collected, and blood samples were taken. The following cardiometabolic risk markers were evaluated: BMI, blood pressure, glucose, insulin, HOMA-IR, triglycerides, LDL, and HDL-cholesterol. From these, a cluster cardiometabolic risk (CCR)-z score was created by summating all z-scores (except insulin and DBP) computed for each risk factor. Data were analyzed using bivariate analysis and multivariable linear regression. In the multivariable models, the first-trimester CCRs was positively associated with overweight/obesity status (β: 3.54, 95%CI: 2.73, 4.36) but inversely related to the level of education (β: −1.04, 95%CI: −1.94, 0.14) and physical activity (PA) (β: −1.21, 95%CI: −2.24, −0.17). The association between overweight/obesity and CCR (β:1.91, 95%CI: 1.01, 2.82) persisted into the third-trimester, whereas insufficient GWG (β: −1.14, 95%CI: −1.98, −0.30) and higher social class (β: −2.28, 95%CI: −3.42, −1.13) were significantly associated with a lower CCRs. Starting pregnancy with normal weight, higher socioeconomic and educational levels, being a non-smoker, non-consumer of alcohol, and PA were protective factors against cardiovascular risk during pregnancy.
Funder
Instituto de Salud Carlos III
Subject
Food Science,Nutrition and Dietetics
Cited by
1 articles.
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