The Role of the Gut Microbiome in Inflammatory Bowel Disease: The Middle East Perspective

Author:

El-Sayed Ahmed1ORCID,Kapila Diya1,Taha Rama Sami Issa2,El-Sayed Sherif3,Mahen Mohd Rafiw Ahmed4,Taha Roa’a2,Alrubaiy Laith25

Affiliation:

1. Hillingdon Hospital NHS Trust, London UB8 3NN, UK

2. Healthpoint Hospital, Abu Dhabi P.O. Box 112308, United Arab Emirates

3. Mid and South Essex NHS Trust, London SS0 0RY, UK

4. Department of Medicine, King’s College Hospital London, Dubai P.O. Box 340901, United Arab Emirates

5. College of Medicine and Health Sciences, Khalifa University, Abu Dhabi P.O. Box 127788, United Arab Emirates

Abstract

The gut microbiome is of paramount importance in preserving internal balance in the gastrointestinal tract; therefore, disruptions in its regulation have been linked to the development of inflammatory bowel disease (IBD). This article explores the intricate details of the gastrointestinal microbiome as it pertains to inflammatory bowel disease (IBD), with an emphasis on the Middle East. The study reviews the typical gut microbiome, modifications in inflammatory bowel disease (IBD), determinants impacting the gut microbiome of the Middle East, and prospective therapeutic interventions.

Publisher

MDPI AG

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